H. Wallweber : rechercher sur Z-Library

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1

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

Hui, Enfu, Cheung, Jeanne, Zhu, Jing, Su, Xiaolei, Taylor, Marcus J., Wallweber, Heidi A., Sasmal, Dibyendu K., Huang, Jun, Kim, Jeong M., Mellman, Ira, Vale, Ronald D.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 5.54 MB

english, 2017

2

Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation

Ferrao, Ryan D, Wallweber, Heidi JA, Lupardus, Patrick J

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 4.71 MB

english, 2018

3

Proteolysis and amino acid recycling during nitrogen deprivation inSchizophyllum commune

Walt W. Lilly, Gerald J. Wallweber, Sean M. Higgins

Journal:

Current Microbiology

Année:

1991

Langue:

english

Fichier:

PDF, 605 KB

english, 1991

4

The Crystal Structures of EDA-A1 and EDA-A2: Splice Variants with Distinct Receptor Specificity

Sarah G Hymowitz, Deanne M Compaan, Minhong Yan, Heidi J.A Wallweber, Vishva M Dixit, Melissa A Starovasnik, Abraham M de Vos

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 337 KB

english, 2003

5

A Tyrosyl-tRNA Synthetase Suppresses Structural Defects in the Two Major Helical Domains of the Group I Intron Catalytic Core

Christopher A. Myers, Gerald J. Wallweber, Rachel Rennard, Yelena Kemel, Mark G. Caprara, Georg Mohr, Alan M. Lambowitz

Journal:

Journal of Molecular Biology

Année:

1996

Langue:

english

Fichier:

PDF, 1.73 MB

english, 1996

6

IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis

Eugene Varfolomeev, John W. Blankenship, Sarah M. Wayson, Anna V. Fedorova, Nobuhiko Kayagaki, Parie Garg, Kerry Zobel, Jasmin N. Dynek, Linda O. Elliott, Heidi J.A. Wallweber, John A. Flygare, Wayne

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

7

The Crystal Structure of A Proliferation-inducing Ligand, APRIL

Heidi J.A. Wallweber, Deanne M. Compaan, Melissa A. Starovasnik, Sarah G. Hymowitz

Journal:

Journal of Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 474 KB

english, 2004

8

Multiple Novel Classes of APRIL-specific Receptor-blocking Peptides Isolated by Phage Display

Nathaniel C. Gordon, Samantha Lien, Jeremy Johnson, Heidi J.A. Wallweber, Thuy Tran, Bridget Currell, Mary Mathieu, Clifford Quan, Melissa A. Starovasnik, Sarah G. Hymowitz, Robert F. Kelley

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2010

9

587 Development of proximity based assay to detect and quantify erbB (or Her) receptor dimerization in formalin fixed-paraffin embedded tissue sections

R. Dua, Y. Shi, A. Mukherjee, N. Glavas, S. GangaKhedkar, H. Pannu, J. Wallweber, P. Chan-Hui, S. Singh

Journal:

European Journal of Cancer Supplements

Année:

2004

Langue:

english

Fichier:

PDF, 146 KB

english, 2004

10

Uptake and translocation of 2-aminoisobutyric acid bySchizophyllum commune

Walt W. Lilly, Sean M. Higgins, Gerald J. Wallweber

Journal:

Experimental Mycology

Année:

1990

Langue:

english

Fichier:

PDF, 737 KB

english, 1990

11

The Crystal Structure of the Catalytic Domain of the NF-κB Inducing Kinase Reveals a Narrow but Flexible Active Site

Gladys de Leon-Boenig, Krista K. Bowman, Jianwen A. Feng, Terry Crawford, Christine Everett, Yvonne Franke, Angela Oh, Mark Stanley, Steven T. Staben, Melissa A. Starovasnik, Heidi J.A. Wallweber, Jia

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 3.99 MB

english, 2012

12

88 POSTER Development of proximity-based immunoassays for activated HER1, HER2, and HER1-HER2 heterodimers in formalin-fixed, paraffin-embedded (FPPE) cells

L. Defazio-Eli, J. Wallweber, K. Frankson, T. Dao-Pick, T. Dang, R. Dua, L. Goodman, G. Parry, J. Winslow

Journal:

European Journal of Cancer Supplements

Année:

2008

Langue:

english

Fichier:

PDF, 58 KB

english, 2008

13

Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design

Wang, Xiaojing, Magnuson, Steven, Pastor, Rich, Fan, Eric, Hu, Huiyong, Tsui, Vickie, Deng, Wei, Murray, Jeremy, Steffek, Micah, Wallweber, Heidi, Moffat, John, Drummond, Jason, Chan, Grace, Harstad,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2013

14

Interaction of Human Telomerase with Its Primer Substrate

Wallweber, Gerald, Gryaznov, Sergei, Pongracz, Krisztina, Pruzan, Ronald

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 255 KB

english, 2003

15

Combination of Antibody That Inhibits Ligand-Independent HER3 Dimerization and a p110 Inhibitor Potently Blocks PI3K Signaling and Growth of HER2+ Breast Cancers

Garrett, J. T., Sutton, C. R., Kurupi, R., Bialucha, C. U., Ettenberg, S. A., Collins, S. D., Sheng, Q., Wallweber, J., DeFazio-Eli, L., Arteaga, C. L.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 773 KB

english, 2013

16

Purification and characterization of the two constitutively produced acid phosphatase isozymes from Schizophyllum commune

Wallweber, Gerald J., Lilly, Walt W.

Journal:

Mycological Research

Année:

1992

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1992

17

Design, Synthesis, and Biological Activity of a Potent Smac Mimetic That Sensitizes Cancer Cells to Apoptosis by Antagonizing IAPs

Zobel, Kerry, Wang, Lan, Varfolomeev, Eugene, Franklin, Matthew C., Elliott, Linda O., Wallweber, Heidi J. A., Okawa, David C., Flygare, John A., Vucic, Domagoj, Fairbrother, Wayne J., Deshayes, Kurt

Journal:

ACS Chemical Biology

Année:

2006

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2006

18

Structure of the pseudokinase-kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition

Lupardus, P. J., Ultsch, M., Wallweber, H., Bir Kohli, P., Johnson, A. R., Eigenbrot, C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2014

19

Evaluation of Assay Technologies for the Identification of Protein–Peptide Interaction Antagonists

Kadkhodayan, Saloumeh, Elliott, Linda O., Mausisa, Grace, Wallweber, Heidi Ackerly, Deshayes, Kurt, Feng, Bainian, Fairbrother, Wayne J.

Journal:

Assay and Drug Development Technologies

Année:

2007

Langue:

english

Fichier:

PDF, 352 KB

english, 2007

20

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2

Wallweber, Heidi J A, Tam, Christine, Franke, Yvonne, Starovasnik, Melissa A, Lupardus, Patrick J

Journal:

Nature Structural and Molecular Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1013 KB

english, 2014

21

Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination

Dueber, E. C., Schoeffler, A. J., Lingel, A., Elliott, J. M., Fedorova, A. V., Giannetti, A. M., Zobel, K., Maurer, B., Varfolomeev, E., Wu, P., Wallweber, H. J. A., Hymowitz, S. G., Deshayes, K., Vuc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2011

22

Engineering an APRIL-specific B Cell Maturation Antigen

Patel, D. R., Wallweber, H. J. A., Yin, J., Shriver, S. K., Marsters, S. A., Gordon, N. C., Starovasnik, M. A., Kelley, R. F.

Journal:

Journal of Biological Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 420 KB

english, 2004

23

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

Pollock, N. I., Wang, L., Wallweber, G., Gooding, W. E., Huang, W., Chenna, A., Winslow, J., Sen, M., DeGrave, K. A., Li, H., Zeng, Y., Grandis, J. R.

Journal:

Clinical Cancer Research

Année:

2015

Fichier:

PDF, 1.16 MB

2015

24

Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors

H. Hu, X. Wang, G. K. Y. Chan, J. H. Chang, S. Do, J. Drummond, A. Ebens, W. Lee, J. Ly, J. P. Lyssikatos, J. Murray, J. G. Moffat, Q. Chao, V. Tsui, H. Wallweber, A. Kolesnikov

Année:

2015

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2015

25

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

Pollock, N. I., Wang, L., Wallweber, G., Gooding, W. E., Huang, W., Chenna, A., Winslow, J., Sen, M., DeGrave, K. A., Li, H., Zeng, Y., Grandis, J. R.

Journal:

Clinical Cancer Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2015

26

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

Hackos, David H., Lupardus, Patrick J., Grand, Teddy, Chen, Yelin, Wang, Tzu-Ming, Reynen, Paul, Gustafson, Amy, Wallweber, Heidi J.A., Volgraf, Matthew, Sellers, Benjamin D., Schwarz, Jacob B., Paole

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.53 MB

english, 2016

27

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP

VUCIC, Domagoj, FRANKLIN, Matthew C., WALLWEBER, Heidi J. A., DAS, Kanad, ECKELMAN, Brendan P., SHIN, Hwain, ELLIOTT, Linda O., KADKHODAYAN, Saloumeh, DESHAYES, Kurt, SALVESEN, Guy S., FAIRBROTHER, Wa

Journal:

Biochemical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 571 KB

english, 2005

28

The Structural Basis for Class II Cytokine Receptor Recognition by JAK1

Ferrao, Ryan, Wallweber, Heidi J.A., Ho, Hoangdung, Tam, Christine, Franke, Yvonne, Quinn, John, Lupardus, Patrick J.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2016

29

Electrophoretic Detection of Multiple Proteases from Schizophyllum commune

Walt W. Lilly, Sean M. Higgins and Gerald J. Wallweber

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 579 KB

english, 1990

30

A GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in vivo Profile

Villemure, Elisia, Volgraf, Matthew, Jiang, Yu, Wu, Guosheng, Ly, Cuong Q., Yuen, Po-wai, Lu, Aijun, Luo, Xifeng, Liu, Mingcui, Zhang, Shun, Lupardus, Patrick J., Wallweber, Heidi J. A., Liederer, Bia

Journal:

ACS Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 541 KB

english, 2016

31

Prolonged Response to Trastuzumab in a Patient With HER2-Nonamplified Breast Cancer With Elevated HER2 Dimerization Harboring an ERBB2 S310F Mutation

Chumsri, Saranya, Weidler, Jodi, Ali, Siraj, Balasubramanian, Sohail, Wallweber, Gerald, DeFazio-Eli, Lisa, Chenna, Ahmed, Huang, Weidong, DeRidder, Angela, Goicocheal, Lindsay, Perez, Edith A.

Journal:

Journal of the National Comprehensive Cancer Network

Année:

2015

Langue:

english

Fichier:

PDF, 199 KB

english, 2015

32

A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain

Wang, Tzu-Ming, Brown, Brandon M., Deng, Lunbin, Sellers, Benjamin D., Lupardus, Patrick J., Wallweber, Heidi J.A., Gustafson, Amy, Wong, Evera, Volgraf, Matthew, Schwarz, Jacob B., Hackos, David H.,

Journal:

Neuropharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 22.32 MB

english, 2017

33

Electrophoretic Detection of Multiple Proteases from Schizophyllum Commune

Lilly, Walt W., Higgins, Sean M., Wallweber, Gerald J.

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 1.25 MB

english, 1990

34

Electrophoretic Detection of Multiple Proteases from Schizophyllum Commune

Lilly, Walt W., Higgins, Sean M., Wallweber, Gerald J.

Journal:

Année:

1990

Fichier:

PDF, 1.25 MB

1990

35

Phase I Study of Ficlatuzumab and Cetuximab in Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Cancer

Bauman, Julie E., Ohr, James, Gooding, William E., Ferris, Robert L., Duvvuri, Umamaheswar, Kim, Seungwon, Johnson, Jonas T., Soloff, Adam C., Wallweber, Gerald, Winslow, John, Gaither-Davis, Autumn,

Journal:

Année:

2020

Fichier:

PDF, 2.03 MB

2020

36

Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1Î± Inhibitory Activity

Beveridge, Ramsay E., Wallweber, Heidi Ackerly, Ashkenazi, Avi, Beresini, Maureen, Clark, Kevin R., Gibbons, Paul, Ghiro, Elise, Kaufman, Susan, LarivÃ©e, Alexandre, Leblanc, Melissa, Leclerc, Jean-Ph

Journal:

ACS Medicinal Chemistry Letters

Année:

2020

Fichier:

PDF, 3.44 MB

2020